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. 2021 Jun 30;13:645649. doi: 10.3389/fnagi.2021.645649

TABLE 1.

Top 10 transcription factors obtained by IRegulon.

Transcription factor NES Target genes
Irf8 8.7502 Parp12, Zbp1, Tlr3, Atf3, Cxcl10, Cd40, Ccr7, Irf7, Ccl6, Ccr2, Tlr2, Mafb, Egr1, Nr3c1, Il33, Tslp, Rsad2
Nfkb2 8.20316 Cxcl10, Egr1, Nfkb1, Cd40, Cxcl1, Il1b, Cxcl3, Tslp, Ccr7, Atf3, Cxcl2, Spib, Smad7, Plscr1, Il23a, Tlr2, Csf1r, Mafb, Il33
Irf7 6, 986 Atf3, Tlr2, Cd40, Zbp1, Il23a, Irf7, Il33, Nr3c1, Cxcl10, Il1b, Tlr3, Parp12, Ccr7, Smad7, Mafb, Csf1r, Plscr1, Nfkb1, Ifng, Ccr2, Egr1, Rsad2, Ccl6, Ccl7, Tslp, Cxcl3, Cxcl1
Homez 4.708 Nr3c1, Egr1, Smad7, Mafb, Atf3, Csf1r, Ccr7, Nfkb1
Cebpb 4.674 Atf3, Smad7, Il23a, Ltf, Ddit3, Spib, Il1b, Ccr7, Cxcl1, Cxcl3, Tslp, Nfkb1, Egr1, Zbp1, Nr3c1, Il33
Pbx1 4.529 Smad7, Egr1, Ccr7, Atf3, Nr3c1, Mafb, Cxcl1, Nfkb1, Il33, Ccr2, Ltf, Ifng, Irg1, Tslp, Parp12, Tlr2, Zbp1, Tlr3, Cxcl3
Yy1 4.118 Egr1, Nr3c1, Tlr2, Mafb, Smad7, Ccr2, Il23a, Atf3, Zbp1
Cebpa 4.080 Il23a, Ddit3, Atf3, Ccr2, Il1b
Tbx5 4.042 Cxcr3, Ddit3, Nfkb1, Irf7, Ccr7, Nr3c1, Smad7, Plscr1, Atf3
Scrt2 3.999 Nfkb1, Ccr7, Nr3c1, Irf7