Figure 2.
UM signature and Risk Model Performance in Cohort I, for all cases and for subgroups by AJCC 8th edition Stage (IA1, IA2 and IA3 pooled as Stage IA). Kaplan-Meier plots of overall survival based on UM signature predictions for patients in Cohort I. Insets in each panel describe univariable and multivariable Hazard Ratios (95% C.I.) for the UM signature, and C-index (95% C.I.) for the multivariable model. When all cases (n=249) were used, the multivariable Cox analysis included ‘Risk+Age+Gender+Stage’; Cox models of stage-specific subgroups included ‘Risk+Age+Gender’. A) All patients, B) AJCC 8th edition Stage IA, C) AJCC 8th edition Stage IB, D) AJCC 8th edition Stage IIA, E) AJCC 8th edition Stage IIB and F) AJCC 8th edition Stage IIIA.