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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: FEBS Lett. 2020 Dec 22;595(8):1025–1061. doi: 10.1002/1873-3468.14024

Figure 5. Defective mitochondrial ribosome assembly and human disease.

Figure 5.

Schematic representation of organs and tissues affected by mutations in mitoribosome components: assembly factors (black), tRNA or rRNA (light blue), mt-SSU proteins (green) and mt-LSU proteins (orange). For clarity, four human body models, generated by using the Complete Anatomy software, are presented.= indicate organs or tissues commonly affected by all the mitoribosome components in the same group, C = Cornelia de Lange syndrome, L = Leigh syndrome, M = MELAS, P= Perrault Syndrome, R = Rett Syndrome.