Table 3.
Effects of test samples in hole cross test.
| Group | Dose (mg/kg) | Number of hole crossed in minutes |
||||
|---|---|---|---|---|---|---|
| 0 min | 30 min | 60 min | 90 min | 120 min | ||
| Tween 80 | 10 mL/kg | 16.33 ± 1.60 | 14.67 ± 1.25 | 15.0 ± 1.00 | 16.67 ± 0.76 | 15.00 ± 0.58 |
| Diazepam | 1 | 19.00 ± 0.86*** | 6.00 ± 1.32*** | 5.67 ± 1.52*** | 5.00 ± 1.00*** | 3.67 ± 0.57*** |
| AEGA | 200 | 16.93 ± 1.11*** | 4.47 ± 0.88*** | 4.12 ± 1.11*** | 3.41 ± 1.70*** | 5.12 ± 0.78*** |
| AEGA | 400 | 22.45 ± 1.42*** | 3.97 ± 0.95*** | 3.10 ± 1.53*** | 2.43 ± 1.77*** | 2.89 ± 0.99*** |
| EEGA | 200 | 20.33 ± 1.45*** | 4.67 ± 1.25*** | 3.00 ± 1.k60*** | 3.33 ± 1.50*** | 5.00 ± 1.00*** |
| EEGA | 400 | 20.68 ± 1.89*** | 3.00 ± 2.17*** | 2.33 ± 1.25*** | 2.33 ± 1.25*** | 3.33 ± 1.25*** |
Results are expressed as mean ± SEM (n = 5) and statistically analyzed using ANOVA followed by Dunnett's comparision test. *p < 0.05, **p < 0.01 ***p < 0.001 have been considered as significant, when compared with control (n = 5). AEGA = aqueous extract of Ganoderma applanatum. EEAA = ethanol extract of Ganoderma applanatum.