Table 6.
Effect of test samples in hot plate test.
| Group | Dose | Response time |
|||||
|---|---|---|---|---|---|---|---|
| 0 min | 30 min | 60 min | 120 min | 180 min | 240 min | ||
| Control | 10 mL/kg | 8.0 ± 0.71 | 9.4 ± 0.51 | 6.8 ± 0.58 | 8.4 ± 0.51 | 10 ± 0.71 | 7.8 ± 0.97 |
| Diclofenac sodium | 10 | 10.6 ± 0.51 | 14.4 ± 0.43*** | 12.6 ± 0.51*** | 13.3 ± 0.68*** | 8.2 ± 0.86 | 8 ± 0.89 |
| AEGA | 200 | 9.4 ± 0.51 | 10.4 ± 1.14 | 12.2 ± 0.58** | 11.00 ± 0.71 | 14 ± 1.41** | 13 ± 0.71** |
| AEGA | 400 | 8.5 ± 0.71 | 11.44 ± 1.6 | 13.54 ± 1.18** | 14.7 ± 1.99*** | 18.28 ± 1.37*** | 11 ± 1.58 |
| EEGA | 200 | 8.1 ± 0.21 | 8.5 ± 1.10 | 11.4 ± 0.40 | 12.5 ± 0.52 | 13.5 ± 1.01** | 13.4 ± 0.53** |
| EEGA | 400 | 9.75 ± 0.11 | 8.1 ± 0.11 | 12.3 ± 0.35** | 13.5 ± 0.41 | 16.31 ± 0.45*** | 12.47 ± 0.81** |
Results are expressed as mean ± SEM (n = 5) and statistically analyzed using ANOVA followed by Dunnett's test. *p < 0.05, **p < 0.01 ***p < 0.001 have been considered as significant, when compared with control. AEGA = aqueous extract of Ganoderma applanatum. EEAA = ethanol extract of Ganoderma applanatum.