Table 7.
Docking scores of the selected compounds of Ganoderma applanatum mushroom with the potassium channel KCSA-FAB (PDB: 4UUJ) and human serotonin transporter (PDB: 5I6X) and Cyclooxygenase-1 (PDB: 2OYE) receptors.
| Docking Score (kcal/mol) | ||||
|---|---|---|---|---|
| Compounds | PubChem CID | Anxiolytic |
Antidepressant |
Analgesic |
| 4UUJ | 5I6X | 2OYE | ||
| Applanatumol E | 132542814 | −7.1 | −6.0 | −6.4 |
| Cytosporone C | 10778975 | −5.7 | −5.8 | −12.8 |
| Nigragillin | 15939563 | −5.7 | −5.2 | −7.3 |
| Ganoapplanin | 11067914 | −10.5 | −6.8 | −7.1 |
| Myrocin C | 132581256 | −7.5 | −6.8 | −7.9 |
| Sphaeropsidin D | 636779 | −7.9 | −10.5 | −6.9 |
| Standard drugs (Diazepam/Diclofenac sodium) | 3016/5018304 | −7.3 | −6.4 | −6.9 |