Table 2.
OCT characteristics according to QFR tertiles.
|
Lowest tertile
(T1, n = 28) |
Middle tertile
(T2, n = 29) |
Highest tertile
(T3, n = 26) |
p-value | ||||
|---|---|---|---|---|---|---|---|
| Overall | T1 vs. T2 | T1 vs. T3 | T2 vs. T3 | ||||
| MLA, mm2 | 2.03 (1.47–2.97) | 2.30 (2.05–3.07) | 3.63 (2.82–4.30) | <0.001 | 0.901 | <0.001 | 0.002 |
| Area stenosis, % | 68.1 ± 12.8 | 60.1 ± 9.0 | 54.2 ± 13.7 | <0.001 | 0.033 | <0.001 | 0.170 |
| Lipid-rich plaques | 28 (100.0) | 23 (79.3) | 23 (88.5) | 0.028 | 0.023 | 0.105 | 0.475 |
| Average lipid arc, ° | 155 (135–202) | 153 (107–185) | 126 (105–165) | 0.019 | 0.606 | 0.015 | 0.433 |
| Maximum lipid arc, ° | 320 (198–360) | 220 (180–300) | 200 (150–310) | 0.017 | 0.086 | 0.025 | 1.000 |
| Lipid length, mm | 18.5 (11.6–22.4) | 12.5 (8.0–21.0) | 12.0 (8.0–18.0) | 0.223 | – | – | – |
| Lipid index, ° × mm | 2,527 (1,973–3,844) | 1,756 (1,085–3,648) | 1,574 (578–2,415) | 0.058 | – | – | – |
| Thinnest FCT, μm | 73 (43–148) | 150 (70–190) | 120 (70–180) | 0.040 | 0.058 | 0.157 | 1.000 |
| TCFAs | 14 (50.0) | 4 (13.8) | 5 (19.2) | 0.005 | 0.003 | 0.018 | 0.721 |
| Plaque rupture | 4 (14.3) | 0 (0.0) | 1 (3.8) | 0.057 | 0.052 | 0.353 | 0.473 |
| Plaque erosion | 6 (21.4) | 1 (3.4) | 3 (11.5) | 0.101 | 0.052 | 0.470 | 0.335 |
| Thrombus | 11 (39.3) | 1 (3.4) | 3 (11.5) | 0.002 | 0.001 | 0.020 | 0.335 |
| Calcification | 14 (50.0) | 14 (48.3) | 9 (34.6) | 0.463 | 0.896 | 0.253 | 0.305 |
| Calcified nodules | 2 (7.1) | 1 (3.4) | 2 (7.7) | 0.735 | 0.611 | 1.000 | 0.598 |
| Microchannels | 9 (32.1) | 9 (31.0) | 11 (42.3) | 0.634 | 0.928 | 0.440 | 0.386 |
| Macrophage accumulation | 15 (53.6) | 9 (31.0) | 10 (38.5) | 0.213 | 0.085 | 0.266 | 0.563 |
| Cholesterol crystals | 10 (35.7) | 11 (37.9) | 8 (30.8) | 0.852 | 0.862 | 0.700 | 0.577 |
Values are expressed as n (%) or mean ± standard deviation or median (interquartile range). FCT, fibrous cap thickness; MLA, minimal lumen area; TCFA, thin cap fibroatheroma; other abbreviations as Table 1.