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. 2021 Jun 30;8:690262. doi: 10.3389/fcvm.2021.690262

Table 3.

IVUS characteristics according to QFR groups.

Low QFR High QFR p-value
Grayscale IVUS lesions (n = 49)
Lesion No. 26 23
Grayscale IVUS findings
  EEM CSA, mm2 12.3 (10.6–14.7) 12.4 (10.8–16.1) 0.515
  Plaque + media, mm2 8.9 (7.5–10.7) 8.7 (7.0–10.3) 0.771
  Plaque burden, % 73.2 (68.0–77.7) 66.5 (64.0–72.9) 0.036
  MLA, mm2 3.5 (2.8–4.1) 4.1 (3.4–4.9) 0.025
  Reference EEM CSA, mm2 13.1 (11.2–14.5) 13.0 (10.3–17.0) 0.528
  Remodeling index 0.96 (0.80–1.10) 0.92 (0.81–1.08) 0.787
  Positive remodeling 11 (42.3) 7 (30.4) 0.390
  Negative remodeling 13 (50.0) 13 (56.5) 0.648
VH-IVUS lesions (n = 40)
Lesion No. 20 20
VH-IVUS findings
  Fibrous tissue, mm2 2.7 (2.0–4.5) 2.7 (1.8–4.0) 0.678
  Fibrous tissue, % 62.9 (52.9–69.5) 56.2 (45.0–62.8) 0.134
  Fibrofatty tissue, mm2 1.0 (0.6–1.8) 1.8 (0.6–2.5) 0.121
  Fibrofatty tissue, % 16.6 (11.7–28.5) 22.7 (17.9–46.8) 0.142
  Necrotic core, mm2 0.7 (0.3–1.2) 0.4 (0.2–1.2) 0.478
  Necrotic core, % 12.2 (7.0–20.8) 9.7 (2.3–21.1) 0.398
  Dense calcium, mm2 0.2 (0.0–0.4) 0.1 (0.0–0.2) 0.398
  Dense calcium, % 3.3 (0.1–7.1) 1.1 (0.0–6.5) 0.565
  VH-TCFA 3 (15.0) 3 (15.0) 1.000

Values are expressed as n (%) or median (interquartile range). CSA, cross-sectional area; EEM, external elastic membrane; VH-IVUS, virtual histology intravascular ultrasound; other abbreviations as Tables 1, 2.