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. 2021 Jun 30;11:702644. doi: 10.3389/fonc.2021.702644

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Copyright © 2021 Wang, Hong, Zhou, Ni, Zhang, Zhao, Wu, Wang, Ding, Chang, Hu and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hematological parameters are correlated with cytokines/serum biochemical markers associated with CRS. (A) An overview of the correlation between minimum hematological parameters after CAR-T cell infusion and peak cytokines or serum biochemical markers associated with CRS. (B–J) Max lg ferritin, IL-10, and IFNγ were most significantly associated with hematological parameters, including neutrophil count (B–D), hemoglobin concentration (E–G), and platelet count (H–J). P values and r values were determined by Spearman correlation analysis. ***P < 0.001, **P < 0.01, *P < 0.05, ns, no significance.