Table 1.
Characteristics of participants.
| CUn = 100 | MCI-DLBn = 17 | MCI-ADn = 41 | P-valuea | |
|---|---|---|---|---|
| Age, yrs | 69.7 (9.4) | 68.6 (5.6) | 70.5 (8.7) | 0.75 |
| Males, no. (%) | 72 (72%) | 17 (100%) | 25 (61%) | 0.004 |
| APOE4, no. (%) | 32 (32%) | 6 (35%) | 28 (70%) | <0.001 |
| Education, yrs | 15.3 (2.7) | 16.2 (2.7) | 16.1 (3.1) | 0.20 |
| CDR Sum of boxes | 0.0 (0.1) | 1.8 (1.0) | 1.7 (1.1) | <0.001 |
| MMSE | 28.7 (0.9) | 27.7 (2.7) | 26.0 (2.7) | <0.001 |
| Follow-up, yrs | 3.2 (1.9) | 2.0 (1.3) | 0.08 | |
| UPDRS Part III | 13.8 (12.1) | 1.0 (2.3) | <0.001 | |
| DRS Total | 135.4 (6.6) | 131.1 (7.6) | 0.049 | |
| Visual Hallucinations, no. (%) | 6 (35%) | 0 (0%) | <0.001 | |
| Fluctuations, no. (%) | 7 (41%) | 0 (0%) | <0.001 | |
| Parkinsonism, no. (%) | 14 (82%) | 3 (7%) | <0.001 | |
| RBD, no. (%) | 15 (88%) | 5 (12%) | <0.001 |
Mean (SD) listed for the continuous variables and count (%) for the categorical variables. UPDRS Total and DRS Total values are not reported in the clinically unimpaired participants from the Mayo Clinic Study of Aging.
CU: clinically unimpaired. CDR: Clinical Dementia Rating Scale, MMSE: Mini-Mental State Examination, UPDRS: Unified Parkinson’s Disease Rating Scale (UPDRS), DRS: Mattis Dementia Rating Scale, pRBD: probable REM Sleep Behavior Disorder.
a
P-values represent an ANOVA test for continuous variables and Fisher’s exact test for categorical variables.