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. 2021 Jul 6;23:101477. doi: 10.1016/j.pmedr.2021.101477

Table 5.

Subgroup analysis on the effect of CBT - based interventions on depressive symptom.

Subgroups Depressive symptom: post- to pre - treatment effect
Studies(n) Participants(n) I2% (P) Q-test MD (95%,CI) SMD (95%,CI) P (between)
Behavioral strategies 0.003
 Important 2 183 0.00 (0.909) 0.01 −1.06 (−2.39, 0.26) −0.21 (−0.50, 0.08)
 Not important 7 1437 99.30 (0.000) 868.70 −3.53 (−4.50, −2.56)*** −1.31 (−2.25, −0.37)**
Cognitive strategies <0.001
 Important 7 1409 99.30 (0.000) 863.37 −3.88 (−4.93, −2.84)*** −1.24 (−2.21, −0.28)*
 Not important 2 211 0.00 (0.673) 0.18 −0.80 (−1.24, −0.36)*** −0.47 (−0.76, −0.19)**
Body directed strategies 0.110
 Important 6 1329 99.30 (0.000) 721.97 −2.80 (−3.79, −1.81)*** −1.01 (−2.03, 0.01)
 Not important 3 291 98.50 (0.000) 133.60 −8.46 (−15.37, −1.55)* −1.18 (−2.38, 0.03)
Homework assignment strategies 0.005
 Important 3 810 82.10 (0.004) 11.14 −0.48 (−1.13, 0.18) −0.31 (−0.63, 0.02)
 Not important 6 810 99.40 (0.000) 833.99 −6.56 (−10.76, −2.35)** −1.44 (−2.48,-0.40)**
Problem solving 0.003
 Important 2 183 0.00 (0.909) 0.01 −1.06 (−2.39, 0.26) −0.21 (−0.50, 0.08)
 Not important 7 1437 99.30 (0.000) 868.70 −3.53 (−4.50, −2.56)*** −1.31 (−2.25, −0.37)**
Dietary intervention 0.006
 Important 4 651 99.30 (0.000) 424.61 −9.96 (−16.87, −3.06)** −1.78 (−2.96, −0.61)**
 Not important 5 969 77.10 (0.002) 17.46 −0.24 (−0.44, −0.04)* −0.44 (−0.84, −0.04)*
Physical activity 0.002
 Important 5 771 99.30 (0.000) 611.22 −7.93 (−12.77, −3.10)** −1.55 (−2.59, −0.50)**
 Not important 4 849 71.30 (0.015) 10.47 −0.15 (−0.32, 0.02) −0.41 (−0.88, 0.07)
Country 0.003
 Developed country 2 183 0.00 (0.909) 0.01 −1.06 (−2.39, 0.26) −0.21 (−0.50, 0.08)
 Developing country 7 1437 99.30 (0.000) 868.70 −3.53 (−4.50, −2.56)*** −1.31 (−2.25, −0.37)**
Treatment form 0.290
 Group 2 691 0.00 (0.589) 0.29 −0.05 (−0.14, 0.03) −0.10 (−0.25, 0.05)
 Individual 3 597 99.30 (0.000) 287.73 −4.63 (−13.10, 3.83) −1.02 (−2.78, 0.74)
Treatment delivery way <0.001
 Remote 2 197 0.00 (0.482) 0.50 −0.71 (−1.70, 0.27) −0.20 (−0.48, 0.08)
 Face to face 7 1423 99.30 (0.000) 868.82 −3.79 (−4.80, −2.79)*** −1.31 (−2.26, −0.37)**
Number of session 0.510
 ≥10 4 851 98.40 (0.000) 186.67 −5.90 (−9.23, −2.58)** −1.08 (−2.11, −0.04)*
 <10 4 649 99.50 (0.000) 661.83 −3.53 (−9.69, 2.63) −1.17 (−2.56, 0.23)
Treatment course 0.040
 ≥12w 4 1170 99.60 (0.000) 824.84 −9.45 (−17.33, −1.57)* −1.42 (−2.93, 0.09)
 <12w 5 450 90.30 (0.000) 41.25 −0.93 (−1.77, −0.10)* −0.76 (−1.34, −0.18)*
Patients with comorbid mood symptoms 0.001
 Yes 4 680 99.50 (0.000) 605.03 −9.72 (−15.45, −3.99)** −1.85 (−2.94, −0.77)**
 No 5 940 66.90 (0.017) 12.09 −0.17 (−0.34, 0.01) −0.37 (−0.75, 0.00)

*P < 0.05, **P < 0.01, ***P < 0.001.

MD = Mean difference; SMD = Standard mean difference.