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. 2021 Jul 6;23:101477. doi: 10.1016/j.pmedr.2021.101477

Table 6.

Subgroup analysis on the effect of CBT - based interventions on anxiety symptom.

Subgroups Anxiety symptom: post- to pre - treatment effect
Studies(n) Participants(n) I2% (P) Q-test MD (95%,CI) SMD (95%,CI) P (between)
Behavioral strategies 0.250
 Important 3 236 96.20 (0.000) 52.80 −5.77 (−10.42, −1.13)* −1.40 (−2.31, −0.49)**
 Not important 7 1437 98.70 (0.000) 479.63 −3.01 (−3.82, −2.20)*** −1.22 (−1.72, −0.73)***
Cognitive strategies 0.002
 Important 8 1462 98.80 (0.000) 591.31 −4.43 (−5.33, −3.53)*** −1.45 (−1.94, −0.97)***
 Not important 2 211 86.70 (0.006) 7.49 −1.26 (−3.01, 0.49) −0.58 (−0.85, −0.30)***
Body directed strategies 0.200
 Important 7 1382 98.30 (0.000) 344.85 −2.85 (−3.60, −2.10)*** −1.18 (−1.57, −0.79)***
 Not important 3 291 99.20 (0.000) 244.65 −7.72 (−15.17, −0.27)* −1.56 (−3.06, −0.05)*
Homework assignment strategies 0.070
 Important 4 875 97.10 (0.000) 102.06 −2.72 (−4.09, −1.35)*** −1.04 (−1.59, −0.48)***
 Not important 6 798 99.00 (0.000) 497.94 −5.82 (−8.85, −2.80)*** −1.43 (−2.03, −0.83)***
Dietary intervention 0.010
 Important 4 651 98.90 (0.000) 279.55 −7.41 (−12.27, −2.55)** −1.60 (−2.48, −0.72)***
 Not important 6 1022 96.20 (0.000) 130.71 −1.32 (−1.85, −0.79)*** −1.05 (−1.44, −0.65)***
Physical activity 0.020
 Important 5 771 99.00 (0.000) 389.78 −5.88 (−9.24, −2.52)** −1.36 (−2.12, −0.60)***
 Not important 5 902 96.90 (0.000) 130.35 −1.69 (−2.33, −1.05)*** −1.18 (−1.66, −0.71)***
Treatment form 0.730
 Group 2 664 98.90 (0.000) 93.37 −6.14 (−17.54, 5.25) −1.59 (−3.25, 0.07)
 Individual 4 677 90.60 (0.000) 31.90 −4.11 (−6.24, −1.99)*** −1.04 (−1.50, −0.57)***
Treatment delivery way 0.650
 Remote 2 197 62.90 (0.101) 2.69 −3.16 (−5.39, −0.94)** −0.72 (−1.01, −0.43)***
 Face to face 8 1476 98.80 (0.000) 580.57 −3.71 (−4.54, −2.89)*** −1.42 (−1.92, −0.93)***
Number of session 0.400
 ≥10 3 759 99.20 (0.000) 250.48 −6.93 (−11.08, −2.78)** −1.65 (−2.92, −0.38)*
 <10 6 794 98.60 (0.000) 349.26 −4.68 (−7.80, −1.57)** −1.26 (−1.70, −0.82)***
Duration of session 0.340
 ≥50 min 5 876 98.90 (0.000) 352.67 −3.45 (−4.36, −2.54)*** −1.71 (−2.60, −0.82)***
 <50 min 2 480 91.50 (0.001) 11.83 −4.84 (−7.56, −2.13)*** −1.36 (−1.80, −0.93)***
Treatment course 0.080
 ≥12w 4 1170 99.30 (0.000) 459.21 −7.23 (−12.16, −2.30)** −1.58 (−2.33, −0.83)***
 <12w 6 503 96.30 (0.000) 134.03 −2.77 (−3.94, −1.60)*** −1.06 (−1.54, −0.59)***
Patients with comorbid mood symptoms 0.000
 Yes 5 745 99.10 (0.000) 462.18 −7.86 (−11.71, −4.01)*** −1.71 (−2.56, −0.86)***
 No 5 928 91.20 (0.000) 45.36 −0.77 (−1.16, −0.38)*** −0.81 (−0.95, −0.68)***

*P < 0.05, **P < 0.01, ***P < 0.001.

MD = Mean difference; SMD = Standard mean difference.