Table 2.

Prediction of Progression-free survival and overall survival (in%) for MRS, ISS and RISS at 1, 2, 3, 4 and 5 years in MMIn (n=1070) and MMRF datasets (n=900).

MMIn dataset
	Year	MRS (n = 1070)			ISS (n = 1070)			RISS (n = 627)
		1	2	3	1	2	3	1	2	3
PFS	1	89.78	85.73	77.11	89.64	88.48	80.24	91.11	86.76	68.24
	2	77.00	71.45	58.46	80.33	73.89	62.68	84.15	72.39	53.41
	3	69.13	54.94	43.02	68.50	62.48	46.22	62.62	58.07	36.87
	4	55.66	40.28	33.60	53.22	49.98	33.48	33.46	45.28	27.44
	5	43.04	33.30	27.48	40.25	41.67	27.22	26.77	36.66	18.29
OS	1	96.75	93.19	86.74	93.64	95.88	89.94	97.78	95.56	82.27
	2	94.39	84.18	71.89	90.10	88.82	78.01	93.28	87.91	70.40
	3	91.72	76.52	63.62	87.84	82.63	69.45	90.76	81.80	59.32
	4	90.58	68.34	55.29	85.82	76.00	61.30	86.98	73.61	49.03
	5	85.82	61.73	48.78	80.94	71.91	52.79	86.98	68.65	40.39

MMRF dataset
	Year	MRS (n = 900)			ISS (n = 900)			RISS (n = 703)
		1	2	3	1	2	3	1	2	3
PFS	1	88.95	77.64	69.84	89.95	79.44	69.08	90.32	80.49	62.03
	2	77.56	59.90	42.20	77.11	61.86	46.24	79.57	61.73	38.13
	3	62.82	42.17	35.10	59.75	48.21	33.6	62.95	47.73	28.99
	4	51.49	28.09	23.16	47.7	32.95	22.35	46.41	33.74	26.36
	5	35.61	24.66	13.89	34.81	29.27	14.37	27.69	24.96	26.36
OS	1	96.93	90.90	82.81	96.76	91.61	85.29	98.07	91.17	83.21
	2	93.73	82.69	66.44	93.91	85.24	68.65	96.11	83.81	61.09
	3	88.43	76.18	59.20	90.73	77.16	60.79	92.86	77.28	49.78
	4	86.56	72.64	51.88	88.21	73.39	55.8	88.33	73.52	47.02
	5	79.06	66.66	41.91	74.73	71.92	48.93	57.48	70.49	35.27