Figure 5.

Characteristics of melanoma primary cell secretome

(A) Frequency of peptides identified only in the secretome of Salmonella-infected (Salm) or untreated (ut) melanoma primary cultures or present in both (common).

(B) Distribution of length, hydrophobicity, and isoelectric point of peptides.

(C) Relative distribution of the secretome’s peptides within the cognate protein sequence.

(D) Frequency of proteins having at least one peptide identified in the secretome.

(E) Distribution of length, hydrophobicity, and isoelectric point of proteins.

In (B)–(E), unique peptides or proteins identified in at least one melanoma patient secretome are reported. In (B) and (E), the violin plots indicate the frequency of the peptides/proteins, with all single peptides/proteins indicated as dots. Red lines indicate the median. See also Figure S7 and Table S2.