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. 2020 Aug 31;8(5):590–602. doi: 10.1016/j.gendis.2020.08.006

Table 1.

Gene regulated by lncRNAs and miRNAs in NK cell development.

LncRNA/MiRNA Target gene Model Biological significance Reference
lnc-CD56 CD56 human enhances the expression of CD56 42
miR-583 IL-2Rγ human acts as a negative regulator of NK cell differentiation by silencing IL2Rγ 46
miR-181 Nemo-like kinase human promotes NK cell development through the suppression of Nemolike-kinase 45
Rroid Id2 mouse regulates the function and lineage identity of NK cells 41
miR-29b TBET, EOMES mouse deletion of miR-29b in NK cells reverses the depletion of NK cell subset in leukemic mice 47
miR-150 c-Myb mouse differentially controls the development of NK cell lineages by targeting c-Myb 44
miR-15/16 c-Myb mouse miR-15/16 regulation of Myb controls the NK cell maturation program 43