Table 3.

Pharmacokinetics (mean C_max and T_max) of tetrahydrocannabinol (THC) and cannabidiol (CBD) in occasional (non-current) users, in blood, after three doses of THC and one dose of CBD.

	Smoked	Vaporised	Oral
THC (10 mg) (Spindle et al., 2018 – smoked and vapourised; Vandrey et al., 2017 – oral)
Cmax (ng/mL)	3.76	7.53	1 a
Tmax (h)	0.11	0.18	0.9 a
THC (25 mg) (Spindle et al., 2018 – smoked and vapourised; Vandrey et al., 2017 – oral)
Cmax (ng/mL)	10.24	14.36	3.5 a
Tmax (h)	0.13	0.19	2.6 a
THC (50.6 mg) (Newmeyer et al., 2016)
THC Cmax (ng/mL)	51.6	47.8	10.3 a
THC Tmax (h)	0.11	0.11	2.3 a
CBD (100 mg) (Spindle et al., 2018)
CBD Cmax (ng/mL)	181.4 b	104.6	11.1
CBD Tmax (h)	0.1	0.1	3

^aOral via a brownie.

^bSmoked a high-CBD-dominant strain, which had 100 mg CBD and 3.7 mg THC.