Table 2.

Population Characteristics and Key Findings in Studies of OXTR rs53576 or rs2254298 and ED behaviour

Review Subsection	Authors	Sample	Summary of Study Findings - rs53576	Summary of Study Findings - rs225498
OXTR Variants and ED	Connelly et al. [54]	Community sample of females	GG genotype more likely to have engaged in vomiting or laxative use as weight loss strategy
	Micali et al. [55]	Community sample of females	A allele negatively correlated to binging/purging behaviours, GG genotype was at increased risk of engaging in binging and purging	A allele carriers at increased odds of restrictive eating/purging A allele carriers who had experienced poor maternal care at increased odds of binging purging
	Kim et al. [56]	Females (age range not specified) with AN, BN and HC	G allele positively associated with BN, stronger association observed in those with AG genotype
	Acevedo et al. [57]	Adult females with AN, BN and HC	Positive association between A allele carriers of either/both SNPs and severity of ED symptomatology In those with previous AN, A allele carrier status increased severity of cognitions and eating behaviours
	Davis et al. [58]	Community sample of adults	No significant effects for either SNP
OXTR and Brain Structure/Function	Sala et al. [59]	Adult females with, or recovered from, AN		Reduced activation of brain areas underpinning social salience and reflection observed in A allele carriers Greater negative connectivity observed in A allele carriers