Table 1.

A longitudinal view of single and multiple fetus clinical pregnancy rates, 2005–2016

Study year	2005	2010	2015	2016	p-value
Clinical pregnancies (%)a	34.5	36.8	29.3	25.4	< 0.0001
Singleton (%)	20.5	23.1	20.4	19.8	< 0.0001
Multiples (%)	11.2	11.5	6.9	5.6	< 0.0001
No pregnancy (%)	65.4	62.4	70.2	72.2	< 0.0001

This table demonstrates that multiple fetus clinical pregnancy rates after 2010 declined more than singleton pregnancies, suggesting a successful national U.S. effort to reduce multiple pregnancies and deliveries

^aWith reference point cycle start