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. 2021 Jul 13;19:211. doi: 10.1186/s12957-021-02326-y

Table 1.

The correlation of tumor size with clinicopathologic characteristics of 943 patients with papillary thyroid carcinoma between 2014 and 2016

Variable Overall PTC (n = 943) PTC > 10 mm (n = 373) PTMC (n = 570) Univariate analysis Multivariate analysis
n (%) n (%) n (%) P P OR(95CI)
Gender
 Male 233 (25) 107 (29) 126 (22) 0.02 0.899 0.98(0.70–1.38)
 Female 710 (75) 266 (71) 444 (78)
Age (years) * (45.9 ± 11.3) (45.4 ± 12.0) (46.3 ± 10.8) 0.265
Focality
 Uni 588 (73) 259 (69) 429 (75) 0.05 0.178 1.25(0.90–1.73)
 Multi 255 (27) 114 (31) 141 (25)
HT
 Yes X50 (5) 15 (4) 35 (6) 0.159
 No 893 (95) 358 (96) 535 (94)
CLNM
 Yes 505 (53) 275 (74) 230 (40) < 0.001 <0.001 4.10(3.04–5.53)
 No 438 (47) 98 (26) 340 (60)
TNM staging
 I 856 (91) 320 (86) 536 (94) < 0.001 0.554 1.19(0.66–2.15)
 II 87 (9) 53 (14) 34 (6)
BRAFV600E mutation
 Yes 806 (85) 311 (83) 495 (87) 0.141
 No 137 (15) 62 (17) 75 (13)

Abbreviations: PTC papillary thyroid carcinoma, PTMC papillary thyroid microcarcinoma, HT Hashimoto’s thyroiditis, CLNM central lymph node metastasis

*Numbers are presented as means ± standard deviation