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. 2021 Jul 13;19:211. doi: 10.1186/s12957-021-02326-y

Table 5.

Stratified analysis on the relationships of BRAFV600E mutation status with age and tumor size of PTC patients

Variable Total PTC PTC > 10 mm group PTMC
Positive Negative Positive Negative Positive Negative
n (%) n (%) P n (%) n (%) P n (%) n (%) P
Age
 ≤ 30 72 (76) 23 (24) 0.08 33 (65) 18 (35) 0.003 39 (88) 5 (12) 0.818
 30~ 154 (86) 25 (14) 57 (85) 10 (15) 97 (87) 15 (13)
 40~ 289 (86) 46 (14) 105 (85) 19 (15) 184 (87) 27 (13)
 50~ 208 (87) 32 (13) 82 (90) 9 (10) 126 (85) 23 (15)
60~ 83 (88) 11 (12) 34 (85) 6 (15) 49 (91) 5 (9)
Tumor size (mm)
 ≤ 5 201 (81) 47 (19) 0.001 201 (81) 47 (19) < 0.001
 5~ 294 (91) 28 (9) 294 (91) 28 (9)
 10~ 152 (86) 24 (14) 152 (86) 24 (14) 0.197
 15~ 77 (84) 15 (16) 77 (84) 15 (16)
 > 20 82 (78) 23 (22) 82 (78) 23 (22)

Abbreviations: PTC papillary thyroid carcinoma, PTMC papillary thyroid microcarcinoma