Table 2.
Levels of SOX2 and OCT4 expression in odontogenic cysts and tumors, based on the semi-quantitative assessment of percentage of positive cells. Analysis of comparison was performed using Kruskal-Wallis test
| Stem cell markers | Odontogenic tumors | Immunohistochemical staining, n (%) | P-value | ||||
|---|---|---|---|---|---|---|---|
| Level 0 | Level 1+ | Level 2+ | Level 3+ | Level 4+ | |||
| SOX2 | AMa | 11 (73.3) | 4 (26.7) | 0 | 0 | 0 | <0.001 |
| AOTb | 5 (100) | 0 | 0 | 0 | 0 | ||
| AFb,c | 0 | 0 | 0 | 3 (60) | 2 (40) | ||
| COCc | 4 (80) | 1 (20) | 0 | 0 | 0 | ||
| DCd | 1 (10) | 6 (60) | 0 | 3 (30) | 0 | ||
| OKCa,d | 0 | 0 | 2 (13.3) | 1 (6.7) | 12 (80) | ||
| OCT4 | AM | 15 | 0 | 0 | 0 | 0 | 0.365 |
| AOT | 5 | 0 | 0 | 0 | 0 | ||
| AF | 5 | 0 | 0 | 0 | 0 | ||
| COC | 5 | 0 | 0 | 0 | 0 | ||
| DC | 10 | 0 | 0 | 0 | 0 | ||
| OKC | 13 (86.7) | 2 (13.3) | 0 | 0 | 0 | ||
Lesion pairs labelled by letters a, b, c and d showed statistically significant differences in expression using post hoc pairwise comparison tests