Fig. 5.

Multi-marker image mass cytometry figures of non-responders (top two images) vs. responders (bottom two images). In left most images, blue staining represents nuclear beta catenin (representing cellular nuclei) and red staining represents CD8 + T-cells. In right most images, blue demonstrates tumour, red demonstrates CD8 + T-cells nad grey demonstrates stoma, showing that the T-cells infiltrate predominantly the stromal compartment. Violin plot to the right shows significant differences between responders and non-responders in terms of percentage of CD8 + T-cells (percentage shown is relative to total number of cells)