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. 2021 Jul 14;21:199. doi: 10.1186/s12906-021-03368-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Effect of Hitrechol® on Organ Index (a), Total Cholesterol Levels (b) and Total Phospholipid Levels (c) of different treatment groups. n = 4 to 6 for each treatment group. Data presented in Mean ± SEM, *p < 0.05 compared to VEH + ND group, ^p < 0.05 compared to H (QD) + ND group, #p < 0.05 compared to VEH + LGD group, +p < 0.05 compared to H(QD) + LGD group analyzed by one-way ANOVA followed by Tukey’s multiple comparisons test. VEH: Vehicle; ND: Normal diet; LGD: Lithogenic diet; H (QD): Hitrechol® once daily; H (TID): Hitrechol® three times daily. VEH + ND: Group 1; VEH + LGD: Group 2; H (QD) + ND: Group 3; H (QD) + LGD: Group 4; H (TID) + LGD: Group 5