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. 2021 Feb 9;24(6):464–476. doi: 10.1093/ijnp/pyab004

Figure 3.

Figure 3.

Blood concentrations of neuroendocrine outcomes during ghrelin and placebo sessions of the i.v. alcohol clamp (IV-AC) experiment. A 10-minute loading dose of i.v. acyl-ghrelin (3 mcg/kg) or placebo was administered, followed by a continuous infusion of acyl-ghrelin (16.9 ng/kg/min) or placebo until the end of each session. Alcohol clamp started at T2 and continued until the end of the session (5 minutes before T4). T0: 5 minutes before the start of the ghrelin/placebo loading dose; T1: at the end of the ghrelin/placebo loading dose and the start of the ghrelin/placebo continuous infusion; T2: 30 minutes after the start of the ghrelin/placebo continuous infusion; T3: 45 minutes after the start of the ghrelin/placebo continuous infusion; T4: 70 minutes after the start of the ghrelin/placebo continuous infusion. Blood concentrations of each hormone per time-point are expressed as mean (M) and standard error of the mean (SEM). For statistical results, see Table 3. Abbreviations: GIP, gastric inhibitory peptide; GLP-1, glucagon-like peptide-1; IGF-1, insulin-like growth factor-1; PP, pancreatic polypeptide.