Table 3.

Correlation between topographic distribution of microbleeds and underlying medical history significant for either CABG, valve replacement or CAA

	Amyloid (n=41)	CABG (n=21)	Valve (n=37)	P value*	CABG-Amyloid†	Valve-Amyloid†	Valve-CABG†
Total CMB	18.0±25.9	3.5±2.3	4.1±4.1	<0.01	<0.01	<0.01	0.99
Cortical	15.5±20.4	2.0±1.0	2.7±2.7	<0.01	<0.01	<0.01	0.98
SWM	1.5±3.0	0.9±0.9	0.8±1.3	0.74	0.87	0.74	0.99
Ratio‡	0.05±0.08	0.26±0.28	0.18±0.17	<0.01	<0.01	0.01	0.25

*P value calculated using ANOVA.

†P value calculated using Tukey honest significant difference test.

‡Ratio=SWM/SWM+cortical microbleeds.

ANOVA, analysis of variance; CAA, cerebral amyloid angiopathy; CABG, coronary artery bypass grafting; CMB, cerebral microbleeds; SWM, subcortical white matter.