Summary of findings 1. Mini‐Cog for the detection of Alzheimer's disease dementia and other dementias within a community setting.
Title: Mini‐Cog for the detection of Alzheimer's disease dementia and other dementias within a community setting | ||||
Population | Community‐dwelling older adults | |||
Setting | Community setting was intended to represent a population based sample of older adults in which the Mini‐Cog may be used as a screening tests. Studies that included populations where participants were identified from community settings but then evaluated using the Mini‐Cog and reference standard were included in the review | |||
Index test | Mini‐Cog either administered as a single test or Mini‐Cog scores for the clock drawing test and three‐word delayed recall were derived from larger tests | |||
Reference Standard | Clinical diagnosis of dementia using any recognized classification system | |||
Studies | Cross‐sectional studies, case control studies were excluded | |||
Study | Accuracy (95% CI) | Number of participants | Dementia prevalence | Implications |
Borson 2000 | Sensitivity: 0.99 (0.96 to 1.00) Specificity: 0.93 (0.87 to 0.97) Positive LR: 14.88 Negative LR: 0.0083 |
249 | 51.8% | Excluded individuals with questionable dementia (CDR = 0.5) from study population, accuracy of Mini‐Cog in diagnosing mild dementia not determined which may have overestimated the accuracy of the Mini‐Cog. The prevalence of dementia is higher than would be anticipiated from most community based studies |
Borson 2003 | Sensitivity: 0.76 (0.65 to 0.85) Specificity: 0.89 (0.87 to 0.91) Positive LR: 6.92 Negative LR: 0.07 |
1119 | 6.8% | Excluded individuals with questionable dementia (CDR = 0.5) from analysis which may have resulted in an overestimation of the accuracy of the Mini‐Cog |
Borson 2005/2006 | Sensitivity: 0.99 (0.95 to 1.00) Specificity: 0.83 (0.76 to 0.89) Positive LR: 5.78 Negative LR: 0.01 |
252 | 44.4% | Individuals referred from community agencies to Alzheimer's centre. The prevalence of dementia is higher that would be expected from most community based studies, which may have affected the test accuracy of the Mini‐Cog |