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. 2021 Jul 14;2021(7):CD010860. doi: 10.1002/14651858.CD010860.pub3

Summary of findings 1. Mini‐Cog for the detection of Alzheimer's disease dementia and other dementias within a community setting.

Title: Mini‐Cog for the detection of Alzheimer's disease dementia and other dementias within a community setting
Population Community‐dwelling older adults
Setting Community setting was intended to represent a population based sample of older adults in which the Mini‐Cog may be used as a screening tests. Studies that included populations where participants were identified from community settings but then evaluated using the Mini‐Cog and reference standard were included in the review
Index test Mini‐Cog either administered as a single test or Mini‐Cog scores for the clock drawing test and three‐word delayed recall were derived from larger tests
Reference Standard Clinical diagnosis of dementia using any recognized classification system
Studies Cross‐sectional studies, case control studies were excluded
Study Accuracy (95% CI) Number of participants Dementia prevalence Implications
Borson 2000 Sensitivity: 0.99 (0.96 to 1.00)
Specificity: 0.93 (0.87 to 0.97)
Positive LR: 14.88
Negative LR: 0.0083
249 51.8% Excluded individuals with questionable dementia (CDR = 0.5) from study population, accuracy of Mini‐Cog in diagnosing mild dementia not determined which may have overestimated the accuracy of the Mini‐Cog. The prevalence of dementia is higher than would be anticipiated from most community based studies
Borson 2003 Sensitivity: 0.76 (0.65 to 0.85)
Specificity: 0.89 (0.87 to 0.91)
Positive LR: 6.92
Negative LR: 0.07
1119 6.8% Excluded individuals with questionable dementia (CDR = 0.5) from analysis which may have resulted in an overestimation of the accuracy of the Mini‐Cog
Borson 2005/2006 Sensitivity: 0.99 (0.95 to 1.00)
Specificity: 0.83 (0.76 to 0.89)
Positive LR: 5.78
Negative LR: 0.01
252 44.4% Individuals referred from community agencies to Alzheimer's centre. The prevalence of dementia is higher that would be expected from most community based studies, which may have affected the test accuracy of the Mini‐Cog