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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Mech Ageing Dev. 2020 Dec 28;194:111425. doi: 10.1016/j.mad.2020.111425

Figure 3 -. Aging causes senescence-related markers in the mouse ovary to increase.

Figure 3 -

qPCR analysis of ovarian Cdkn1a (p21), Cdkn2a (p16), PAI-1 and HMGB1 reveal age-related increases in all markers by 9 and/or 12 months of age as compared to younger animals (3 and/or 6 months of age) (n=10/group, one-way ANOVA, *p<0.05, **p<0.01, ***p<0.001 SNK post hoc).