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. 2021 Jul 14;10(7):e1305. doi: 10.1002/cti2.1305

Figure 1.

Figure 1

CTL, CD4+ Tconv and NK1.1+ cells are instrumental in spontaneous rejection of breast cancer NOP23. (a) NOP23 tumor growth (mean ± SEM) in the mammary fat pad of female mice treated or not with anti‐CD8β or anti‐NK1.1 mAb at the indicated time (arrows) with the first injection given 1 day before tumor engraftment. One experiment representative of at least 2 independent ones with 5 mice per group is shown. (b) NOP23 tumor growth (mean ± SEM) in female mice treated or not with anti‐CD4 (once a week) or anti‐CTLA‐4 (every 3 days) mAb at the indicated time (arrows) with the first injection given 1 day before tumor engraftment. n = 7 mice per group. *, P < 0.05; **, P < 0.01; and ***, P < 0.001; unpaired t‐test.