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. 2021 Jul 6;14:779–814. doi: 10.2147/CCID.S315711

Table 2.

Selection Criteria

Condition Contraindication (CI) or Physician Discretion (PD) Timing to Filler Rx Suggestions
Chemotherapy CI on Rx > 6m after completion Immunosuppression documented 6 months after adjuvant Rx; Consider psychological needs. Informed consent.
Radiotherapy PD > 6 m Vigilant follow-up
Immunotherapy PD; Postpone Insistent pt with subsequent LOAEs: No systemic steroids!
Rx: AB, ± I/L steroids
Caution: tumor - mimicking filler types (scans)
Previous LOAE 1 m after full clearance Exclude previous trigger factors
Acne Pre-Rx Clearance Topical: Pre-Rx entire acne area
Increased resistant P acnes at edge of topically Rx area; No safe distance
Rosacea Barrier Fx decreased 1–3 m
Perioral dermatitis 6 weeks
Dermatitis Barrier Fx decreased 1 m after clearance Caution: allergies, staph carriers, eczema herpeticum
Autoimmune collagenoses Active: CI Check parameters; Rheumatology consult
Rheumatoid Arthritis Active: CI Stable: skin test before injection
Systemic lupus erythematosus Active: CI Stable: skin test before injection
Mixed Connective Tissue Disease CI
Thyroid Hashimoto: CI Burnt-out Hashimoto’s: may treat
Diabetes PD Decreased tissue healing
Active HSV CI Prophylaxis: start 1-day pre-Rx
Full 5 days of Rx
Infective until last crust disappeared
HSV prophylaxis pre-procedural
Treatment history? Resistance
Porphyria PD drug intolerances Caution: treatment of potential A/E’s - drug C/I’s
Pregnancy CI No safety data; Medicolegal implications
Lactation PD
Body dysmorphic disorder PD Complications
Transgender (Transitioning) Psychiatric counselling, informed consent and photo-documentation
Hormone-induced acne, especially female to male transitioning
HIV PD Full-blown AIDS: CI
Chronic urticaria CI
Severe allergies (multiple) PD 2–4 weeks between Enquire re vaccination protocols
Vaccinations COVID-19 SARS2 Filler and vaccination
(Unknown: suggested 2-4 weeks)
Prophylactic lisinopril may be attempted
  1. in LOAE-prone patients

  2. before 2nd vaccination, if reaction occurred after first vaccination

Abbreviations: CI, contraindicated; PD, physician discretion; AB, antibiotics; I/L, intralesional; m, month; A/E, adverse events; LOAE, late onset adverse events; AIDS, acquired immunodeficiency syndrome.