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. 2021 Jul 14;22:204. doi: 10.1186/s12931-021-01792-y

Fig. 2.

Fig. 2

Cellular mechanism for SPMs in pulmonary disease. Specialized pro-resolving mediators (SPMs) contributed to the resolution of inflammation. These endogenous mediators involved in cytokines production, pathways regulation and inflammatory cell modulation, which can affect different pathophysiologic process of these pulmonary diseases. There is the major regulation pathway of SPMs in tuberculosis, asthma, COPD, cystic fibrosis and pneumonia and bronchopulmonary dysplasia