Table 4.
Enriched GO terms of up and down-regulated transcripts in LEU (n = 4) compared with CON (n = 4) pigs
| GO ID | Go term | Genes count | P value | Fold enrichment |
|---|---|---|---|---|
| Down-regulated Go terms | ||||
| Biological process | ||||
| GO:0031297 | Replication fork processing | 3 | 0.009 | 20.9 |
| GO:0000724 | Double-strand break repair via homologous recombination | 4 | 0.012 | 8.36 |
| GO:0019915 | Lipid storage | 3 | 0.033 | 10.5 |
| Cellular component | ||||
| GO:0005654 | Nucleoplasm | 24 | 0.001 | 2.07 |
| GO:0042555 | MCM complex | 3 | 0.002 | 47.5 |
| GO:0000790 | Nuclear chromatin | 7 | 0.002 | 5.18 |
| GO:0015630 | Microtubule cytoskeleton | 5 | 0.006 | 6.71 |
| GO:0005730 | Nucleolus | 13 | 0.012 | 2.27 |
| GO:0005689 | U12-type spliceosomal complex | 3 | 0.026 | 11.9 |
| GO:0000785 | Chromatin | 4 | 0.027 | 6.09 |
| GO:0005578 | Proteinaceous extracellular matrix | 6 | 0.033 | 3.35 |
| GO:0000783 | Nuclear telomere cap complex | 2 | 0.037 | 52.8 |
| GO:0005814 | Centriole | 4 | 0.043 | 5.11 |
| Molecular function | ||||
| GO:0003678 | DNA helicase activity | 3 | 0.001 | 63.3 |
| GO:0003723 | RNA binding | 7 | 0.023 | 3.16 |
| GO:0008270 | Zinc ion binding | 16 | 0.046 | 1.70 |
| GO:0003729 | mRNA binding | 4 | 0.050 | 4.69 |
| Up-regulated Go terms | ||||
| Cellular component | ||||
| GO:0070062 | Extracellular exosomes | 17 | 0.035 | 1.69 |
| Molecular function | ||||
| GO:0003697 | Single-stranded DNA binding | 3 | 0.031 | 10.6 |