Table 1. IC50 Values of Compounds 1–6 on a Selected Panel of Cancer Cell Lines.
IC50 (μM)a |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Compd. | NCI-H460 | H1299 | SKOV-3 | DU145 | MCF7 | MCF10A | MB-MDA-231 | SF268 | HT-29 | HCT-15 |
1 | 40.52 | >100 | 27.85 | 32.67 | 22.36 | >100 | 57.12 | >100 | >100 | >100 |
2 | >100 | >100 | 56.18 | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
3 | >100 | >100 | >100 | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
4 | 44.77 | >100 | 20.15 | >100 | 41.34 | >100 | 68.12 | >100 | >100 | >100 |
5 | >100 | >100 | >100 | >100 | 88.1 | >100 | >100 | >100 | >100 | >100 |
6 | 40.32 | 90.81 | >100 | 13.06 | 16.75 | 88.63 | 21.60 | 38.8 | 36.42 | 54.12 |
Data from ref (101).