Table 5:
Correlation of immune infiltrate and pathologic lymph node stage.
| CIBERSORT ANALYSIS | |||
|---|---|---|---|
| LN Stage | OR | 95% CI | p value |
| Naïve B cells | 1.1 | 1.0–1.1 | 5.2 × 10−4 |
| Memory B cells | 1.1 | 0.97–1.2 | 0.16 |
| Plasma cells | 1.0 | 0.98–1.1 | 0.30 |
| CD8 T cells | 1.0 | 0.96–1.0 | 0.83 |
| Resting CD4 memory T cells | 1.0 | 0.99–1.1 | 0.20 |
| Activated CD4 memory T cells | 0.97 | 0.78–1.2 | 0.82 |
| Follicular helper T cells | 1.0 | 0.96–1.1 | 0.55 |
| Regulatory T cells | 1.0 | 0.92–1.1 | 0.91 |
| Gamma delta T cells | 1.1 | 0.97–1.2 | 0.18 |
| M0 macrophages | 1.0 | 1.0–1.1 | 0.021 |
| M1 macrophages | 1.0 | 0.94–1.1 | 0.89 |
| M2 macrophages | 1.0 | 0.97–1.0 | 0.87 |
| Resting dendritic cells | 1.1 | 1.0–1.1 | 0.019 |
| Activated dendritic cells | 1.1 | 0.99–1.2 | 0.076 |
| Neutrophils | 1.9 | 1.0–4.1 | 0.067 |
| TIMER ANALYSIS | |||
| LN Stage | OR | 95% CI | p value |
| DCs | 3.4 | 1.9–6.3 | 5.5 × 10−5 |
| CD8 T cells | 2.1 | 1.1–4.0 | 0.029 |
| CD4 T cells | 0.69 | 0.087–5.4 | 0.72 |
| Macrophages | 0.59 | 0.15–2.2 | 0.43 |
| B cells | 2.3 | 1.0–5.7 | 0.054 |
| Neutrophils | 10.5 | 2.7–44 | 8.7 × 10−4 |