Table 2.
Predictors of Disease‐Free Survival After Radiofrequency Ablation
| Characteristic | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR | P Value | HR | P Value | |
| Male/female | 1.00 (0.79‐1.28) | 0.992 | 1.08 (0.84‐1.40) | 0.524 |
| Age <65 years | 0.94 (0.75‐1.19) | 0.606 | 0.98 (0.77‐1.26) | 0.908 |
| HCV | 1.19 (0.94‐1.53) | 0.158 | 1.09 (0.85‐1.41) | 0.512 |
| Child‐Pugh class A/B | 0.57 (0.44‐0.76) | <0.001 | 0.60 (0.45‐0.80) | 0.001 |
| ALBI grade | ||||
| 1/2 | 0.54 (0.43‐0.69) | <0.001 | ||
| 2/3 | 0.81 (0.32‐1.67) | 0.597 | ||
| AFP >100 ng/mL | 1.30 (0.96‐1.75) | 0.090 | 1.15 (0.84‐1.56) | 0.360 |
| No‐touch procedure | 0.45 (0.33‐0.61) | <0.001 | 0.59 (0.42‐0.82) | 0.002 |
| Safety margin >5 mm | 0.58 (0.46‐0.73) | <0.001 | 0.76 (0.57‐1.00) | 0.053 |
| Coverage of the entire blood drainage area | 0.55 (0.44‐0.69) | <0.001 | 0.76 (0.58‐0.99) | 0.049 |
| Tumor diameter <2 cm | 1.02 (0.81‐1.31) | 0.842 | 1.02 (0.80‐1.33) | 0.834 |
| Single tumor | 0.60 (0.19‐3.66) | 0.514 | 0.29 (0.09‐1.80) | 0.154 |
| Surface | 1.24 (0.73‐2.11) | 0.432 | 1.20 (0.91‐1.59) | 0.199 |
| Major vessel involvement | 1.18 (0.86‐1.66) | 0.310 | 1.32 (0.96‐1.88) | 0.088 |
Abbreviations: AFP, alpha‐fetoprotein; HCV, hepatitis C virus.