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. 2021 Jun 17;64(13):9193–9216. doi: 10.1021/acs.jmedchem.1c00403

Figure 9.

Figure 9

Effect of sLXm (R)-6 on murine zymosan-induced peritonitis. Mice were pretreated with (R)-6 (2 μg/kg and 6 μg/kg) or Dex (1 mg/kg) by ip injection 30 min prior to zymosan (40 mg/kg) administration and again 1 h after zymosan injection. Peritoneal cells were collected by lavage 24 h after zymosan injection. (a) Graphs and dot-plots show PMN counts corresponding to Ly6G+ cells. Surface marker expression on peritoneal cells was assessed by flow cytometry. One-way analysis of variance (ANOVA) statistical analysis was performed, *p < 0.05. (b) Table displays the absolute count and relative % of maximal response. Data are presented as mean ± SEM, n = 5 mice/treatment group.