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. 2021 Aug 1;12(5):1211–1222. doi: 10.14336/AD.2020.1221

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copyright: © 2021 Xue et al.

this is an open access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — ICAM1 in HBMECs were upregulated after exosome treatment. (A) The number of tubes was detected by immune-histochemical staining (CD31). (B) The quantitative results (P<0.05). (C) Immunohistochemical staining results for the expression of ANGPT1 with control and exosomes stimulus. (D) The expression of FLK1 was detected using immunohistochemical with control and exosomes stimulus. (E-F) Proteomics and time series analysis of the target protein ICAM1, which was highly expressed after exosome stimulus. (G) The formation of tubes by HBMECs with or without ICAM1 knockdown.