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. 2021 May 3;4(3):e00251. doi: 10.1002/edm2.251

TABLE 1.

Eligible high‐risk HLA genotypes for the enrolment in the TEDDY study

TEDDY Code Full Genotype Abbreviation General population
A DRB1*04‐DQA1*03:01‐DQB1*03:02/DRB1*03‐DQA1*05:01‐DQB1*02:01 DR3/DR4 Yes
B DRB1*04‐DQA1*03:01‐DQB1*03:02/DRB1*04‐DQA1*03:01‐DQB1*03:02 1 DR4/DR4 Yes
C DRB1*04‐DQA1*03:01‐DQB1*03:02/DRB1*08‐DQA1*04:01‐DQB1*04:02 DR4/DR8 Yes
D DRB1*03‐DQA1*05:01‐DQB1*02:01/DRB1*03‐DQA1*05:01‐DQB1*02:01 DR3/DR3 Yes
E DRB1*04‐DQA1*03:01‐DQB1*03:02/DRB1*04‐DQA1*03:01‐DQB1*02:01 DR4/DR4 No
F DRB1*04‐DQA1*03:01‐DQB1*03:02/DRB1#‐DQA1*01:01‐DQB1*05:01 2 DR4/DR1 No
G DRB1*04‐DQA1*03:01‐DQB1*03:02/DRB1*13‐DQA1*01:02‐DQB1*06:04 DR4/DR13 No
H DRB4*01‐ DQA1*03:01‐DQB1*03:02/ DRB1*04‐DQA1*03:01‐DQB1*03:04 DR4/DR4 No
I DRB1*04‐DQA1*03:01‐DQB1*03:02/RB1*09‐DQA1*03:01‐DQB1*03:03 DR4/DR9 No
J DRB1*03‐DQA1*05:01‐DQB1*02:01/DRB1*09‐DQA1*03:01‐DQB1*03:03 DR3/DR9 No

The DR4 subtypes DRB1*0403 were excluded. 1 Acceptable alleles in this haplotype include both DQB1*0302 and *0304. 2 In this DQB1*0501 haplotype, DR10 must be excluded. Only DR1 is eligible.