TABLE 3.
Change in factors associated with change in BMI% exceeding the 95th percentile, HOMA‐IR, Adiponectin and TG to HDL Ratio (A) Sex, Age and BMI Z‐Score Adjusted; (B) Adjusted for sex, age, BMI Z‐Score and respective change in ‘BMI% exceeding the 95th percentile’ or change in measures of insulin sensitivity
| Full sample | Parameter estimate | t value | p‐value |
|---|---|---|---|
| (A) | |||
| Δ BMI% exceeding the 95th percentile | (n = 33, R 2 = .507, p = .007) | ||
| Δ Factor 2: BCAA‐related and uric acid | 3.416 | 3.45 | .0020 |
| Δ Factor 7: Urea cycle amino acids and HIS | −1.964 | −2.31 | .0294 |
| Δ Factor 8: Short‐chain acylcarnitines | −3.064 | −2.79 | .0099 |
| Δ Factor 10: Large neutral amino acids and CRP | 2.736 | 2.13 | .0436 |
| Δ HOMA‐IR | (n = 33, R 2 = .297, p = .075) | ||
| Δ Factor 3: Medium‐chain acylcarnitines | −0.168 | −2.09 | .0461 |
| Δ Factor 5: Long‐chain acylcarnitines | −0.332 | −2.66 | .0129 |
| Δ Adiponectin | (n = 33, R 2 = .497, p = .002) | ||
| Δ Factor 6: Medium‐chain acylcarnitines | 0.096 | 2.81 | .0091 |
| Δ Factor 7: Urea cycle amino acids and HIS | 0.082 | 2.53 | .0174 |
| Δ TG to HDL Ratio | (n = 33, R 2 = .166, p = .2607) | ||
| Δ Factor 2: BCAA‐related and uric acid | 0.194 | 2.22 | .0319 |
| (B) | |||
| Δ BMI% exceeding the 95th percentile | (n = 33, R 2 = .460, p = .008) | ||
| Δ HOMA‐IR | 4.329 | 2.31 | .0239 |
| Δ Factor 2: BCAA‐related and uric acid | 2.878 | 2.78 | .0099 |
| Δ Factor 8: Short‐chain acylcarnitines | −2.560 | −2.87 | .0081 |
| Δ HOMA‐IR | (n = 33, R 2 = .495, p = .009) | ||
| Δ BMI% exceeding the 95th percentile | 0.031 | 2.38 | .0255 |
| Δ Factor 3: Medium‐chain acylcarnitines | −0.164 | −2.31 | .0294 |
| Δ Factor 5: Long‐chain acylcarnitines | −0.307 | −2.62 | .0149 |
| Δ Factor 8: Short‐chain acylcarnitines | 0.183 | 2.46 | .0211 |
| Δ Adiponectin | (n = 33, R 2 = .497, p = .004) | ||
| Δ BMI% exceeding the 95th percentile | 0.002 | 0.26 | .7946 |
| Δ Factor 6: Medium‐chain acylcarnitines | 0.097 | 2.77 | .0103 |
| Δ Factor 7: Urea cycle amino acids and HIS | 0.084 | 2.46 | .0207 |
| Δ TG to HDL Ratio | (n = 33, R 2 = .168, p = .388) | ||
| Δ BMI% exceeding the 95th percentile | −0.003 | −0.23 | .8186 |
| Δ Factor 2: BCAA‐related and uric acid | 0.204 | 2.11 | .0447 |
Sex, age and BMI z‐score are included in all linear regression models; however, only statistically significant variables are reported. The p‐value included in the parentheses under the parameter estimate column refers to the overall model fit (F statistics).
Sex, age and BMI z‐score are included in all linear regression models; however, only statistically significant variables are reported. In addition, change in BMI% exceeding the 95th percentile model adjusted for change in HOMA‐IR and change in measures of insulin sensitivity models adjusted for change in BMI% exceeding the 95th percentile. The p‐value included in the parentheses under the parameter estimate column refers to the overall model fit (F statistics).