In vitro activation of splenocytes from Cxcl17−/− mice or WT littermates revealed higher production of key activation cytokines by Cxcl17−/− leukocytes including (A) IFN-γ, TNF-α, and IL-2 and (B) CXCL9, CXCL10, CCL3, and CCL4 chemokines. Student’s t-test was performed. All values are means ± SEM. Means with asterisks are significantly different (*P < 0.1, **P < 0.01). Data are representative from 3 or more individual experiments