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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Neurobiol Learn Mem. 2020 Dec 4;177:107358. doi: 10.1016/j.nlm.2020.107358

Table 2.

ChABC treatment altered membrane properties of rat DCN neurons.

Vm (mV) Input Res
(MΩ)		 AP threshold
(mV)		 Current required
for evoked AP
(nA)		 Latency
(ms)		 Amplitude
(mV)		 APD50
(ms)		 APD50
rising
(ms)		 APD50
falling
(ms)		 AHP (mV) S1S2
interval
(ms)
Vehide −46.93 ± 0.82 132.95 ± 15.6 −47.90 ± 1.84 0.02 ± 0.01 20.27 ± 4.19 69.92 ± 3.38 1.04 ± 0.16 0.40 ± 0.05 0.64 ± 0.12 −8.88 ± 1.36 17.83 ± 3.14
ChABC −46.40 ± 0.69 124.03 ± 1.07 −42.71 ± 0.94** 0.04 ± 0.01** 45.99 ± 9.51* 70.62 ± 2.19 0.97 ± 0.05 0.38 ± 0.02 0.59 ± 0.03 −12.46 ± 1.12* 31.2 ± 5.00*

Vehicle: Medium treatment; ChABC: ChABC treatment.

Cell number (n) for Vehicle and ChABC was 16, and 22, respectively. Cells from 5 rats.

Note that there were group differences in threshold, current required for evoked AP, latency for evoked AP, AHP amplitude, and S1S2 interval.

*, **

indicate p < 0.05, 0.01, respectively.

AP: Action potential; AP duration was measured at the width of 50% AP duration (APD50); AHP: Afterhyperpolarization; Input Res: Input resistance.