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. 2021 Jun 29;12:643501. doi: 10.3389/fmicb.2021.643501

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Copyright © 2021 Chotirat, Nekkab, Kumpitak, Hietanen, White, Kiattibutr, Sa-angchai, Brewster, Schoffer, Takashima, Tsuboi, Harbers, Chitnis, Healer, Tham, Nguitragool, Mueller, Sattabongkot and Longley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association between village-level PCR prevalence and adjusted P. vivax sero-prevalence. P. vivax sero-prevalence was predicted by the algorithm incorporating antibody responses to the panel of eight P. vivax proteins, using the 62% sensitivity, 90% specificity target. The estimates were adjusted, at the village-level, for to account for the known sensitivity and specificity. A Pearson r correlation was performed to assess the association between PCR prevalence and adjusted P. vivax sero-prevalence. Data passed the Anderson–Darling test for normality.