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. 2021 Jul 7;16(7):e0252700. doi: 10.1371/journal.pone.0252700

Table 6. Detail of treatment and follow-up of young infants with PSBI signs according to their clinical sub-categories (N = 370).

Parameters Total PSBI cases Critical illness (CI) Clinical severe infection (CSI)* Fast breathing only (7–59 days)
A. Case Management and outcome of the PSBI cases who were treated at a government primary health facility (PHC and CHC)
4.1. Number of PSBI cases treated n = 150 n = 6 n = 120 n = 24
4.2. No of PSBI cases who completed recommended simplified antibiotic treatment 68(45.3) 2(33.3) 47(39.2) 19(79.2)
4.3. Doses of antibiotic received—Gentamicin
 • 7 injections 58(38.7) 3(50.0) 55(45.8) -
 • ≥2<7 injections 24(16.0) 2(33.3) 21(17.5) 1(4.2)
 • 1 injection 6(4.0) 1(16.7) 5(4.2) -
 • 0 injection 62(41.3) 0(0.0) 39(32.5) 23 (96)
4.4 Doses of antibiotic received—Amoxicillin
 • 14 doses 102(68.0) 4(66.7) 79(65.8) 19(79.2)
 • 7–13 doses 22(14.7) 0(0.0) 17(14.2) 5(20.8)
 • ≥1< 7 doses 4(2.7) 1(16.7) 3(2.5) 0(0.0)
 • 0 dose of amoxicillin 22(14.7) 1(16.7) 21(17.5) 0(0.0)
4.5. Follow-up visits of PSBI cases during treatment (simplified antibiotic regimen)
 • Follow-up on Day 4 117(78.0) 6(100) 93(77.5) 18(75.0)
 • Completed all follow-up visits (Day 4 and Day 7) 92(61.3) 4(66.7) 77(64.2) 11(45.8)
 • Partial followed-up (Either day 4 or Day 7) 26(17.3) 2(33.3) 17(14.2) 7(29.2)
 • No follow-up 32(21.3) 0(0.0) 26(21.7) 6(25.0)
4.6. Treatment outcomes for PSBI cases (simplified antibiotic regimen)
 • Declared as ‘Clinical treatment success’ 145(96.7) 6(100.0) 116(96.7) 23(95.8)
 • Declared as ‘Clinical treatment failure’ 4(2.7) 0(0.0) 3(2.5) 1(4.2)
 • Death 1(0.7) 0(0.0) 1(0.8) 0(0.0)
B. Treatment outcome of PSBI cases treated at the District hospital/Tertiary Hospital (based on follow up on day 14 after diagnosis of the illness) n = 65 n = 19 n = 39 n = 7
 • Recovered 61(93.8) 16(84.2) 38(97.4) 7(100)
 • Still sick 2(3.1) 1(5.3) 1(2.6) -
 • Outcome unknown - - - -
 • Died 2(3.1) 2(10.5) - -
C. Treatment outcome of PSBI cases treated by a private provider (based on follow up on day 14 after diagnosis of the illness)  § n = 155
 • Recovered 154(99.4) - - -
 • Still sick - - - -
 • Outcome unknown 1(0.6) - - -
 • Died - - - -

*Includes one infant 0–6 days old with fast breathing (severe pneumonia)

†One fast breathing only (7–59 days) case received injection gentamicin

Definition of Treatment Failure: the appearance of any new sign of CI or CSI up to day 8 of treatment (worsening) or persistence of all presenting signs of CSI or CI on day 4 or persistence of any presenting sign by day 8 of treatment

§Case classification was not known for cases managed at a private facility