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. 2021 Jun 30;12:696791. doi: 10.3389/fimmu.2021.696791

Table 1.

A summary of Phase I and II peptide-based cancer vaccine clinical trials currently active or recruiting.

Condition Peptide Vaccine Type NCT number
Adenocarcinoma HER2/neu Peptides NCT02795988
  Personalised Peptide Vaccine NCT04627246, NCT02600949
Bladder Cancer Personalised Peptide Vaccine NCT03359239
Blood Cancer & Leukaemia Multiple Peptides NCT04051307
  Personalised Peptide Vaccine Combination Therapy NCT04688385, NCT03559413, NCT02802943
  WT1 Peptides NCT04747002, NCT03761914
  IDO Peptides NCT03939234
  Survivin Peptides NCT02334865
Brain Cancer TAA Peptide Combination Therapy NCT01795313
  IDH1 Peptide NCT02193347
Breast Cancer Folate Receptor Peptide Combination Therapy NCT02593227, NCT03012100
  HER2/neu Peptides NCT02636582, NCT00194714, NCT04144023, NCT04024800, NCT04197687, NCT03384914
  Novel Peptides NCT02826434, NCT03362060
  Personalised Peptide Vaccine Combination Therapy NCT03606967, NCT02427581
  ESR1 Peptide NCT04270149
Cervical & Ovarian Cancers HPV E6/E7 Liposomes Combination Therapy NCT04580771
  WT1 Peptides NCT02737787
Colorectal Cancer MUC1 Peptides NCT02134925
Gastric Cancer Multiple Peptides Combination Therapy NCT03784040
Glioblastoma CMV Peptide targets NCT02864368
  Novel Peptides NCT04116658
  Personalised Peptide Vaccine NCT03223103
  Survivin Peptides NCT02455557
  Telomerase-derived Peptides NCT04280848
Glioma Neoantigen Peptides NCT04749641, NCT02358187, NCT01130077
  Neoantigen Combination Therapy NCT03893903, NCT02960230
  Multiple Peptides Combination Therapy NCT02924038
Head & Neck Cancers IDO Peptides NCT04445064
Kidney Cancer Personalised Peptide Vaccine Combination Therapy NCT02950766
Liver Cancer PKA Peptide Combination Therapy NCT04248569
Lung Cancer (inc. NSCLC) MUC1 Peptides NCT03300817, NCT01720836
  P10s-PADRE Peptide NCT02264236
  Telomerase-derived Peptides NCT01789099, NCT02818426
  Neoantigen Peptides NCT04487093
  Personalised Peptide Vaccine NCT04397926
Lymphoma Novel Peptides NCT04669171
  Personalised Peptide Vaccine Combination Therapy NCT03361852
Melanoma BRAF/CD4 Epitopes NCT04364230
  CD4+ Epitope peptides NCT03617328
  Novel Peptides NCT02126579
  NY-ESO & gp100 Peptide Combination Therapy NCT01176474, NCT01176461
  IDO & PD-L1 Peptide Combination Therapy NCT03047928
  Personalised Peptide Vaccine Combination Therapy NCT04072900
Multiple Cancers & Solid Tumours Arginase-1 Peptide NCT03689192
  HER2/neu Peptides NCT01376505
  KRAS Peptide Combination Therapy NCT04117087
  Multiple Peptides NCT04316689
  Personalised Peptide Vaccine NCT03715985
  Personalised Peptide Vaccine Combination Therapy NCT03633110, NCT04266730
  Survivin Peptides Combination Therapy NCT03879694
  Telomerase-derived Peptides Combination Therapy NCT03946358
Myeloma Novel Peptide Combination Therapy NCT02886065
  PD-L1 Peptides NCT03850522
Pancreatic Cancer Neoantigen Peptides NCT03956056
  Personalised Peptide Vaccine NCT03558945
Prostate Cancer Bcl-xl Peptides NCT03412786
  Novel Peptide-Conjugate NCT04701021
  RhoC Peptide NCT04114825
  TARP Peptide NCT02362464
  Telomerase-derived Peptides NCT01784913