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BLZ-100 (Tozuleristide, Tumor Paint™). Schematic* of the peptide CTX (targeting motif; gray) labeled with Cy5.5 (dye; green) (A). Intraoperative glioblastoma imaging with 18 mg total BLZ-100 administered 4 h prior to surgery: white-light only (B), NIRF only (C) and white-light with NIRF overlay (D). Ex vivo imaging, white-light with NIRF overlay (E). Panels (B–E) are adapted from (48) with permission. *Not to scale.
