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BBN-IRdye800CW. Chemical structure; BBN(7-14) (ligand) and NOTA (Chelator) in black, IRdye800CW (dye) in green (A). Intraoperative glioblastoma multiforme imaging with 1 mg total BBN-IRdye800CW administered 16 h prior to surgery: NIRF prior to resection (B), residual fluorescence after initial tumor removal (C) and tumor-cavity after complete resection (D). Panels (B–D) are adapted from (53) with permission.
