Table 1.
Characteristic | Value |
---|---|
Total patients, n | 99 |
Sex, n | |
Female | 48 |
Male | 51 |
Median age in years at transplant (range) | 55 (20-74) |
Diagnosis, n | |
Acute lymphoblastic leukemia | 13 |
Acute myeloid leukemia | 61 |
Myelodysplastic syndrome | 25 |
Disease Risk Index, n | |
Low | 3 |
Intermediate | 61 |
High | 32 |
Very High | 3 |
Donor type, n | |
Matched related donor | 39 |
Matched unrelated donor | 51 |
Mismatched related donor | 3 |
Mismatched unrelated donor | 6 |
Graft source, n | |
Bone marrow | 1 |
Peripheral blood stem cells | 98 |
Conditioning intensity, n | |
Myeloablative | 44 |
Reduced intensity/non-myeloablative | 55 |
GVHD prophylaxis backbone, n | |
Cyclosporine/methotrexate | 8 |
Cyclosporine/mycophenolate mofetil | 2 |
Tacrolimus/methotrexate | 63 |
Tacrolimus/sirolimus | 9 |
Tacrolimus/sirolimus/methotrexate | 17 |
ATG for GVHD prophylaxis, n | |
Yes | 25 |
No | 74 |
CMV reactivation | |
Total, n | 27 |
Before day +100, n | 18 |
Before day +30, n | 4 |
Abbreviations: ATG: anti-thymocyte globulin; GVHD: graft-versus-host disease;