Table 2.
The immunologic characteristics in the participants with and without depression-anxiety status.
| Characteristic | Patients with depression-anxiety symptom (N = 20) | Patients without depression -anxiety symptom (N = 37) | P |
|---|---|---|---|
| CD4+/CD8+ | 2.48 (1.24) | 2.13 (1.01) | 0.255 |
| CD3+ | 76.98 (72.40–79.87) | 75.50 (65.24–83.17) | 0.367 |
| CD4+ | 51.92 (8.27) | 42.90 (12.21) | 0.005 |
| CD8+ | 23.53 (8.14) | 23.77 (9.16) | 0.922 |
| IL-2 | 2.48 (2.27–2.69) | 2.50 (2.29–2.73) | 0.913 |
| IL-4 | 2.14 (0.77) | 2.14 (0.81) | 0.997 |
| IL-6 | 4.63 (2.87–16.46) | 11.16 (3.92–28.63) | 0.048 |
| IL-10 | 3.25 (1.33) | 3.02 (0.68) | 0.481 |
| IFN-γ | 2.23 (1.25) | 1.97 (0.69) | 0.387 |
| TNF-α | 2.27 (0.95) | 2.94 (1.32) | 0.050 |
Abbreviations: CD, cluster of differentiation; IL, Interleukin; IFN-γ, Interferon-γ; TNF-α, Tumor Necrosis Factor-α.
Normally distributed data (CD4+/CD8+, CD4+, CD8+, IL-4, IL-10, IFN-γ, TNF-α) were expressed as mean and standard deviation; while data (CD3+, IL-2, IL-6) were expressed as median and interquartile range.
P values indicated the comparison between patients with and without depression-anxiety status.
Differences between two groups were tested using t-test for normally distributed data and the non-normal distributed data were analyzed by Mann-Whitney U test.
The results of cytokines (IL-2, IL-4, IL-6, IL-10, IFN-γ, TNF-α) are expressed in pg/ml; the results of T cells (CD3+, CD4+, CD8+) are expressed in cells/l.