TABLE 4.

Comparative epinephrine concentrations

		Epinephrine
		Nominal Time Post Start of Iontophoresis (min)
		0	11	15	25	35	45	60	90	120	180	240
Formulation	Statistic	Concentration (pg/ml)
2% Lidocaine/1:100,000 Epinephrine	N	14	13	12	11	11	10	13	12	11	11	11
	Mean	30.2	26.3	28.4	28.2	28.9	30.0	28.7	23.1	25.0	28.5	30.8
	SD	20.0	15.9	12.4	17.5	17.4	13.3	14.6	13.1	11.0	8.04	10.1
	Min	0	0	0	0	0	0	0	0	0	20.2	21.5
	Median	32.2	22.9	27.6	29.2	29.1	30.2	25.7	22.5	23.5	27.6	28.4
	Max	64.7	58.9	48.1	53.4	49.1	47.8	61.1	40.3	41.9	47.2	49.1
	CV%	66.3	60.4	43.6	62.0	60.2	44.3	50.9	56.6	43.9	28.2	32.9
	Geo Mean	NC	NC	NC	NC	NC	NC	NC	NC	NC	27.6	29.5
	CV% Geo Mean	NC	NC	NC	NC	NC	NC	NC	NC	NC	25.9	30.9
2% Lidocaine	N	10	9	9	9	9	8	5	4	5	6	5
	Mean	38.1	21.7	24.3	28.6	27.9	31.6	23.8	20.5	22.0	35.0	33.0
	SD	33.2	22.8	21.1	23.4	16.8	16.1	14.9	14.4	13.1	11.5	8.40
	Min	0	0	0	0	0	0	0	0	0	20.4	22.7
	Median	25.8	29.6	28.4	37.3	37.0	33.6	23.3	25.5	27.5	36.5	33.9
	Max	97.9	61.9	58.2	58.4	43.5	54.8	36.9	30.9	32.8	48.6	44.5
	CV%	87.0	105	86.7	81.9	60.2	50.8	62.7	70.2	59.6	33.0	25.4
	Geo Mean	NC	NC	NC	NC	NC	NC	NC	NC	NC	33.3	32.2
	CV% Geo Mean	NC	NC	NC	NC	NC	NC	NC	NC	NC	37.1	26.5