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. 2021 Jul 15;138:104224. doi: 10.1016/j.mvr.2021.104224

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — Several biomarkers for endothelial dysfunction and the outcome of COVID-19. Patients presenting with a higher plasma levels of (A) von Willebrand Factor (VWF) antigen; (B) tissue-type plasminogen activator (t-PA); (C) plasminogen activator inhibitor-1 antigen (PAI-1) antigen; and (D) soluble thrombomodulin (sTM) have an increased risk of composite poor outcome.