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Symptoms and signs of opioid-induced bowel dysfunction
| Heartburn and/or acid reflux |
| Postprandial epigastric distention |
| Epigastric pain |
| Sensation of slow and/or incomplete digestion |
| Nausea and/or vomiting |
| Bloating and/or flatulence |
| Abdominal pain |
| Hard stools |
